Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134733 | 0.94 | KMT2A (0.66) | MEN1KMT2APKMSMN1; SMN2PSMB5 | |
| SCHEMBL4158853 | 0.89 | KMT2A (0.57) | MEN1KMT2APKMTP53NAAA | |
| SCHEMBL4158947 | 0.89 | KMT2A (0.57) | MEN1KMT2APKMTP53NAAA | |
| SCHEMBL4158848 | 0.89 | KMT2A (0.57) | MEN1KMT2APKMTP53NAAA | |
| SCHEMBL12786271 | 0.86 | MEN1 (0.56) | MEN1KMT2APKMSMN1; SMN2PSMB5 | |
| SCHEMBL9502670 | 0.84 | MALT1 (0.55) | MEN1KMT2A | |
| SCHEMBL30132781 | 0.84 | MALT1 (0.55) | MEN1KMT2A | |
| SCHEMBL10693686 | 0.84 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29521788 | 0.84 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5176114 | 0.84 | BCHE (0.60) | MEN1KMT2ARAB9ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376852-B1 | MICROGRANULES ESSENTIALLY CONSISTING OF TRIGLYCERIDES OF SATURATED FATTY ACIDS LOADED WITH AN ACTIVE SUBSTANCE, AND THEIR TOPICAL THERAPEUTICAL USE | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-06-23 | — | — | EP | claimed |
| EP-0376852-A1 | Microgranules essentially consisting of triglycerides of saturated fatty acids loaded with an active substance, and their topical therapeutical use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1990-07-04 | — | — | EP | claimed |