Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654073 | 0.85 | EPHX2 (0.40) | MAPTNPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL5674606 | 0.85 | MAPT (0.44) | MAPTNPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL8494650 | 0.84 | SMN1; SMN2 (0.47) | MAPTNPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL28915433 | 0.82 | NPC1 (0.46) | MAPTNPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL8148677 | 0.82 | ESR1 (0.52) | CYP1A2MEN1KMT2AESRRGLMNA | |
| SCHEMBL1492728 | 0.82 | CYP2C19 (0.50) | MAPTCYP1A2KMT2AALDH1A1TSHR | |
| SCHEMBL10796095 | 0.81 | CYP2C9 (0.58) | NPC1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL4514966 | 0.81 | MEN1 (0.40) | NPC1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL15827159 | 0.81 | CYP26B1 (0.40) | NPC1RAB9ACYP1A2MEN1KMT2A | |
| SCHEMBL20556837 | 0.81 | MIF (0.48) | MAPTNPC1RAB9ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |