SCHEMBL9501941

SCHEMBL9501941

NCCOc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.62
CYP1A2 P05177 3/20 0.62
LMNA P02545 3/20 0.62
MAPK1 P28482 2/20 0.62
PGR P06401 2/20 0.62
SLC6A2 P23975 2/20 0.62
CYP2C19 P33261 2/20 0.62
ALDH1A1 P00352 1/20 0.62
CYP2D6 P10635 1/20 0.62
PDE4A P27815 1/20 0.62
HRH1 P35367 1/20 0.62
HTT P42858 1/20 0.62
SLC6A3 Q01959 1/20 0.62
PDE4D Q08499 1/20 0.62
GAA P10253 2/20 0.58
MEN1 O00255 1/20 0.58
USP2 O75604 1/20 0.58
KMT2A Q03164 1/20 0.58
KEAP1 Q14145 1/20 0.58
NFE2L2 Q16236 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12743862 0.91 LMNA (0.69) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL545524 0.90 HPGD (0.68) HPGDCYP1A2LMNAMAPK1PGR
Hydrochloric Acid SCHEMBL8356286 0.89 HPGD (0.57) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL21880203 0.88 HPGD (0.66) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL30538665 0.88 HPGD (0.66) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL551152 0.88 HPGD (0.66) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL5028940 0.88 LMNA (0.66) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL29530425 0.87 GAA (0.65) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL126798 0.87 GAA (0.65) HPGDCYP1A2LMNAMAPK1PGR
SCHEMBL561993 0.86 HPGD (0.68) HPGDCYP1A2LMNAMAPK1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4874803-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY PENNWALT CORPORATION (US) 1989-10-17 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0308886-A2 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-29 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed