Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 5/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | LAP3 | P28838 | 3/20 | 0.34 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375640 | 0.86 | PPID (0.39) | PPIDADAM17MMP1MMP3MMP9 | |
| SCHEMBL13879602 | 0.77 | PPID (0.44) | PPIDTAS1R3TAS1R1CADL3MBTL1 | |
| SCHEMBL20221812 | 0.73 | PPID (0.40) | PPIDADAM17MMP1MMP3MMP9 | |
| SCHEMBL18270584 | 0.73 | PPID (0.40) | PPIDADAM17MMP1MMP3MMP9 | |
| SCHEMBL10974177 | 0.72 | ALDH1A1 (0.43) | PPIDMMP1MMP3CADL3MBTL1 | |
| SCHEMBL10974215 | 0.72 | ALDH1A1 (0.43) | PPIDMMP1MMP3CADL3MBTL1 | |
| SCHEMBL18512760 | 0.72 | PPID (0.42) | PPIDADAM17MMP1MMP3MMP9 | |
| SCHEMBL7376495 | 0.72 | ALDH1A1 (0.43) | ADAM17MMP1MMP3MMP9LAP3 | |
| SCHEMBL7376499 | 0.72 | ALDH1A1 (0.43) | ADAM17MMP1MMP3MMP9LAP3 | |
| SCHEMBL17198435 | 0.71 | PPID (0.41) | PPIDADAM17MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320118-B1 | PEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-4935404-A | ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1990-06-19 | — | — | US | disclosed |
| EP-0320118-A2 | Peptides with collagenase inhibiting activity | BEECHAM GROUP PLC (GB) | 1989-06-14 | — | — | EP | disclosed |