Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.41 |
| ▸ | GAA | P10253 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GPR39 | O43194 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527268 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL9501969 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL13698792 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL11213005 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3527266 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL11213002 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3278077 | 0.82 | NOX1 (0.48) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL11190662 | 0.80 | MAPT (0.55) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4538133 | 0.80 | MAPT (0.55) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4538128 | 0.80 | MAPT (0.55) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385336-B1 | PROCESSES FOR THE PREPARATION OF PTERIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-06-02 | — | — | EP | claimed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | claimed |
| EP-0385336-B1 | PROCESSES FOR THE PREPARATION OF PTERIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |