Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.41 |
| ▸ | GAA | P10253 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GPR39 | O43194 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527268 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL9501969 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL9501971 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL11213005 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3527266 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL11213002 | 1.00 | NOX1 (0.43) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3278077 | 0.82 | NOX1 (0.48) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL11190662 | 0.80 | MAPT (0.55) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4538133 | 0.80 | MAPT (0.55) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4538128 | 0.80 | MAPT (0.55) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582799-B2 | Method for producing hydrazone derivatives | SHIRATORI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-01 | — | — | US | disclosed |
| US-20090076305-A1 | METHOD FOR PRODUCING HYDRAZONE DERIVATIVES | SHIRATORI PHARMACEUTICAL CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076305-A1 | METHOD FOR PRODUCING HYDRAZONE DERIVATIVES | CYP3A5, DHPS, ALDH5A1 | NOX1 655/4885MAPT 2697/4885GAA 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.