Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254044 | 0.81 | TBXA2R (0.49) | CNR1TBXA2RALDH1A1TSHRPKM | |
| SCHEMBL9266948 | 0.81 | TBXA2R (0.49) | CNR1TBXA2RALDH1A1TSHRPKM | |
| SCHEMBL9254047 | 0.81 | TBXA2R (0.49) | CNR1TBXA2RALDH1A1TSHRPKM | |
| SCHEMBL9738306 | 0.81 | TBXA2R (0.48) | TBXA2RALDH1A1KDM4ETSHRPKM | |
| SCHEMBL9252366 | 0.80 | MMP1 (0.48) | TBXA2RALDH1A1TSHRPKMTHRB | |
| SCHEMBL9260852 | 0.78 | TSHR (0.50) | TBXA2RALDH1A1TSHRPKMTHRB | |
| SCHEMBL9260856 | 0.78 | TSHR (0.50) | TBXA2RALDH1A1TSHRPKMTHRB | |
| SCHEMBL9255832 | 0.78 | TBXA2R (0.50) | TBXA2RALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL9505643 | 0.76 | TBXA2R (0.52) | CNR1TBXA2RALDH1A1KDM4ETSHR | |
| SCHEMBL9257708 | 0.75 | THRB (0.58) | TBXA2RALDH1A1KDM4ETSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361113-B1 | SULFONAMIDOALKYL CYCLOALKANE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | Roche Diagnostics GmbH (DE) | 1993-07-07 | — | — | EP | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |
| EP-0361113-A1 | Sulfonamidoalkyl cycloalkane compounds, processes for their production and pharmaceutical preparations | Roche Diagnostics GmbH (DE) | 1990-04-04 | — | — | EP | disclosed |