Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502331 | 1.00 | ACAT1 (0.54) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502150 | 0.94 | ACAT1 (0.53) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502435 | 0.93 | ACAT1 (0.52) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9505662 | 0.93 | ACAT1 (0.56) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502446 | 0.93 | ACAT1 (0.56) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502235 | 0.93 | ACAT1 (0.56) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9692486 | 0.93 | ACAT1 (0.56) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502752 | 0.89 | ALDH1A1 (0.45) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502420 | 0.89 | ACAT1 (0.58) | ACAT1ALDH1A1HDAC3HDAC1NPC1 | |
| SCHEMBL9502195 | 0.88 | ACAT1 (0.57) | ACAT1ALDH1A1HDAC3HDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |