Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917902 | 0.94 | LMNA (0.60) | LMNATSHRMAPK1ATMTDP1 | |
| SCHEMBL3917903 | 0.94 | LMNA (0.60) | LMNATSHRMAPK1ATMTDP1 | |
| SCHEMBL29861210 | 0.89 | LMNA (0.65) | LMNATSHRTDP1PGRCYP17A1 | |
| SCHEMBL9500269 | 0.84 | LMNA (0.50) | LMNAPGRLPLLIPGALDH1A1 | |
| SCHEMBL1607138 | 0.82 | LMNA (0.75) | LMNATSHRTDP1L3MBTL1PGR | |
| SCHEMBL9498547 | 0.81 | RARB (0.53) | LMNATSHREGFRPTGS2ALDH1A1 | |
| SCHEMBL9498632 | 0.81 | LMNA (0.56) | LMNATDP1PGRCYP17A1FAAH | |
| SCHEMBL13849288 | 0.81 | ESR1 (0.56) | LMNATSHRTDP1PGRCYP17A1 | |
| SCHEMBL25620711 | 0.81 | MAPK1 (0.47) | LMNATSHRMAPK1ATMTDP1 | |
| SCHEMBL12101296 | 0.81 | TDP1 (0.47) | LMNATSHRMAPK1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |