Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921442 | 0.93 | LMNA (0.62) | LMNAPGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL874873 | 0.93 | LMNA (0.62) | LMNAPGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4576404 | 0.93 | LMNA (0.62) | LMNAPGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29861210 | 0.91 | LMNA (0.65) | LMNAPGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1607138 | 0.83 | LMNA (0.75) | LMNAPGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13849288 | 0.83 | ESR1 (0.56) | LMNAPGRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9771901 | 0.83 | LMNA (0.75) | LMNAPGRMAPTSMN1; SMN2CYP17A1 | |
| SCHEMBL7140169 | 0.81 | LMNA (0.54) | LMNAPGRALDH1A1MAPTGRIA4 | |
| SCHEMBL11312030 | 0.81 | LMNA (0.54) | LMNAPGRFFAR1SMN1; SMN2TDP1 | |
| SCHEMBL9502184 | 0.81 | LMNA (0.54) | LMNAPGRALDH1A1SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |