Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512731 | 1.00 | TRPM8 (0.54) | TRPM8CTRB1ITGB3ITGA2BPPARA | |
| SCHEMBL9634168 | 0.92 | TRPM8 (0.58) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL7418088 | 0.89 | TRPM8 (0.61) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL7430937 | 0.89 | TRPM8 (0.61) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL7245549 | 0.89 | TRPM8 (0.61) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL6350990 | 0.89 | TRPM8 (0.61) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL7414480 | 0.89 | TRPM8 (0.61) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL11419293 | 0.87 | TRPM8 (0.57) | TRPM8CTRB1ITGB3ITGA2BCTSB | |
| SCHEMBL9510605 | 0.87 | MME (0.55) | CTSBCTSLCTSSCTSK | |
| SCHEMBL9509483 | 0.87 | MME (0.55) | CTSBCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332999-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5157143-A | DIASTEREOSELECTIVE PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PEPTIDE DERIVATIVES | ZAMBON GROUP S.P.A. (IT) | 1992-10-20 | — | — | US | disclosed |
| EP-0341462-B1 | DIASTEREOSELECTIVE PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PEPTIDE DERIVATIVES | ZAMBON GROUP S.p.A. (IT) | 1992-09-09 | — | — | EP | disclosed |
| US-5028626-A | Peptides with pharmaceutical activity | ZAMBON GROUP S.P.A. (IT) | 1991-07-02 | — | — | US | disclosed |
| EP-0341462-A1 | Diastereoselective process for the preparation of intermediates useful for the synthesis of peptide derivatives | ZAMBON GROUP S.p.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| EP-0332999-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |