Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499472 | 1.00 | TRPM8 (0.53) | TRPM8SPPL2ACTRB1ALDH1A1CYP1A2 | |
| SCHEMBL9499470 | 1.00 | TRPM8 (0.53) | TRPM8SPPL2ACTRB1ALDH1A1CYP1A2 | |
| SCHEMBL9633578 | 0.92 | TRPM8 (0.52) | TRPM8SPPL2ACTRB1ALDH1A1CYP1A2 | |
| SCHEMBL6350990 | 0.88 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1CTSBCTSL | |
| SCHEMBL7414480 | 0.88 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1CTSBCTSL | |
| SCHEMBL7430937 | 0.88 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1CTSBCTSL | |
| SCHEMBL7418088 | 0.88 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1CTSBCTSL | |
| SCHEMBL7245549 | 0.88 | TRPM8 (0.61) | TRPM8CTRB1ALDH1A1CTSBCTSL | |
| SCHEMBL9509435 | 0.86 | MME (0.54) | CTSBCTSLCTSKCA5A | |
| SCHEMBL11419293 | 0.86 | TRPM8 (0.57) | TRPM8CTRB1ALDH1A1MAPTCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332999-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-09-29 | — | — | EP | disclosed |
| EP-0333000-B1 | PEPTIDES WITH INHIBITORY ACTIVITY OF ENZYMATIC SYSTEMS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5157143-A | DIASTEREOSELECTIVE PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PEPTIDE DERIVATIVES | ZAMBON GROUP S.P.A. (IT) | 1992-10-20 | — | — | US | disclosed |
| EP-0341462-B1 | DIASTEREOSELECTIVE PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF PEPTIDE DERIVATIVES | ZAMBON GROUP S.p.A. (IT) | 1992-09-09 | — | — | EP | disclosed |
| US-5145872-A | PEPTIDES WITH PHARMACEUTICAL ACTIVITY | ZAMBON GROUP, S.P.A. (IT) | 1992-09-08 | — | — | US | disclosed |
| US-5028626-A | Peptides with pharmaceutical activity | ZAMBON GROUP S.P.A. (IT) | 1991-07-02 | — | — | US | disclosed |
| EP-0341462-A1 | Diastereoselective process for the preparation of intermediates useful for the synthesis of peptide derivatives | ZAMBON GROUP S.p.A. (IT) | 1989-11-15 | — | — | EP | disclosed |
| EP-0332999-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |
| EP-0333000-A2 | Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them | ZAMBON GROUP S.p.A. (IT) | 1989-09-20 | — | — | EP | disclosed |