Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9503007 | 0.86 | MGAM (0.49) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9518606 | 0.85 | GAA (0.64) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9505234 | 0.83 | GAA (0.61) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL9501356 | 0.79 | NR3C2 (0.54) | NR3C2 | |
| SCHEMBL9504261 | 0.74 | MGAM (0.66) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL7467561 | 0.72 | CACNA1F (0.64) | — | |
| SCHEMBL8258493 | 0.70 | MAPK1 (0.53) | NR3C2 | |
| SCHEMBL10894470 | 0.70 | CACNA1C (0.62) | GAANR3C2 | |
| SCHEMBL10364560 | 0.69 | — | — | |
| SCHEMBL13587735 | 0.69 | NR3C2 (0.60) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| WO-1990009376-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-23 | — | — | WO | disclosed |