SCHEMBL950228

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14665424	1.00	CYP19A1 (0.48)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL28223461	0.89	CYP19A1 (0.54)	CYP19A1ATMGRM1POLBEPHX2
	SCHEMBL14665410	0.86	CYP19A1 (0.52)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL950697	0.86	CYP19A1 (0.52)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL952638	0.84	CYP19A1 (0.48)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL17550548	0.80	CYP19A1 (0.47)	CYP19A1ATMGRM1ALDH1A1EPHX2
	SCHEMBL12705300	0.80	CYP19A1 (0.47)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL17550594	0.79	CYP19A1 (0.46)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL950537	0.79	CYP19A1 (0.43)	CYP19A1ATMGRM1TDP1L3MBTL1
	SCHEMBL4657482	0.78	CYP19A1 (0.56)	CYP19A1ATMGRM1POLBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.