Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502292 | 1.00 | MMP1 (0.41) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL9502477 | 0.90 | MMP9 (0.42) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL9502445 | 0.90 | MMP9 (0.42) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL9502182 | 0.89 | MMP1 (0.40) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL9502092 | 0.89 | MMP1 (0.40) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL9502367 | 0.89 | MMP1 (0.41) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL9502428 | 0.89 | MMP1 (0.41) | MMP1ANPEPERAP2MMP3MMP9 | |
| SCHEMBL7321498 | 0.84 | MMP1 (0.39) | MMP1MMP3MMP9ADAM17 | |
| SCHEMBL7321534 | 0.84 | MMP1 (0.39) | MMP1MMP3MMP9ADAM17 | |
| SCHEMBL7276267 | 0.83 | MMP1 (0.41) | MMP1ANPEPERAP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320118-B1 | PEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0320118-B1 | PEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-4935404-A | ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1990-06-19 | — | — | US | disclosed |