Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 9/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502361 | 0.87 | CYP19A1 (0.57) | HTR2AALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL28813072 | 0.83 | HRH1 (0.58) | HTR2AMEN1KMT2AHTR6HRH1 | |
| SCHEMBL4731450 | 0.82 | POLB (0.68) | HTR2AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31595698 | 0.82 | POLB (0.68) | HTR2AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7753094 | 0.81 | HTR6 (0.69) | HTR2AALDH1A1HTTKMT2AHTR6 | |
| Hydrochloric Acid SCHEMBL7674266 | 0.81 | POLB (0.67) | HTR2AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8986547 | 0.80 | HTR6 (0.67) | HTR2AKMT2AHTR6HRH1POLB | |
| SCHEMBL13621791 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL8758865 | 0.80 | ALDH1A1 (0.62) | HTR2AALDH1A1HTTKMT2AHTR6 | |
| SCHEMBL8758329 | 0.78 | HTR2A (0.53) | HTR2AALDH1A1MEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255335-B1 | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-1071664-A1 | SUBSTITUTED 2-OXO-ALKANOIC ACID- 2-(INDOL-3-YL)-ETHYL] AMIDES | BAYER AG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054301-A1 | SUBSTITUTED 2-OXO-ALKANOIC ACID-[2-(INDOL-3-YL)-ETHYL] AMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |
| US-5480983-A | ANALGESICS, HYPOTENSIVE AGENTS | LABORATOIRES UPSA (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0623138-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNION PHARMA SCIENT APPL (FR) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014102-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRES UPSA (FR) | 1993-07-22 | — | — | WO | disclosed |
| US-5229505-A | CNS and cardiovascular effects | LABORATOIRES UPSA (FR) | 1993-07-20 | — | — | US | disclosed |