Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502433 | 1.00 | POLB (0.30) | POLBHPGDKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9503337 | 0.95 | THRA (0.33) | — | |
| SCHEMBL9503330 | 0.95 | THRA (0.33) | — | |
| SCHEMBL9505822 | 0.91 | POLB (0.34) | POLBHPGD | |
| SCHEMBL9506496 | 0.91 | POLB (0.40) | POLBHPGD | |
| SCHEMBL9506489 | 0.91 | POLB (0.40) | POLBHPGD | |
| SCHEMBL9505831 | 0.91 | POLB (0.34) | POLBHPGD | |
| SCHEMBL9502586 | 0.90 | PKM (0.41) | POLBHPGD | |
| SCHEMBL9502582 | 0.90 | PKM (0.41) | POLBHPGD | |
| SCHEMBL9506503 | 0.89 | HTT (0.42) | POLBHPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364548-B1 | OCTAFLUOROBIPHENYLS | MERCK PATENT GmbH (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0364548-A1 | OCTAFLUOROBIPHENYLS. | MERCK PATENT GMBH (DE) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989009203-A1 | OCTAFLUOROBIPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-10-05 | — | — | WO | disclosed |