Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506099 | 0.88 | GAA (0.51) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9503973 | 0.87 | ACAT1 (0.60) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9502303 | 0.86 | ACAT1 (0.61) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9505632 | 0.86 | ACAT1 (0.51) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9503112 | 0.86 | ACAT1 (0.51) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9361640 | 0.82 | ACAT1 (0.68) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9505636 | 0.81 | ACAT1 (0.45) | GAAMAPTACAT1CNR2POLB | |
| SCHEMBL9365175 | 0.80 | MEN1 (0.54) | SMPD1GAAMAPTACAT1CNR2 | |
| SCHEMBL9503199 | 0.80 | HPGD (0.47) | GAAMAPTACAT1POLBMEN1 | |
| SCHEMBL9504110 | 0.79 | ACAT1 (0.59) | SMPD1MAPTACAT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |