Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 4/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502303 | 0.94 | ACAT1 (0.61) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9503973 | 0.93 | ACAT1 (0.60) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9504006 | 0.91 | ACAT1 (0.49) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9506172 | 0.91 | ACAT1 (0.49) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9502436 | 0.88 | ACAT1 (0.61) | ACAT1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9505632 | 0.85 | ACAT1 (0.51) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9503112 | 0.85 | ACAT1 (0.51) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9503964 | 0.83 | ACAT1 (0.43) | ACAT1L3MBTL1HPGDNAAAMLYCD | |
| SCHEMBL9502971 | 0.82 | ACAT1 (0.59) | ACAT1L3MBTL1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9506162 | 0.82 | ACAT1 (0.59) | ACAT1L3MBTL1HPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |