Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 11/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 11/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 11/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 11/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.56 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23016392 | 0.94 | KEAP1 (0.57) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL24340632 | 0.92 | KEAP1 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL16326257 | 0.92 | KEAP1 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL12954012 | 0.85 | KEAP1 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL15680573 | 0.85 | KEAP1 (0.66) | KEAP1NFE2L2HDAC3HDAC4HDAC1 | |
| SCHEMBL5242576 | 0.80 | HDAC3 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL8847557 | 0.79 | KEAP1 (0.60) | KEAP1NFE2L2EPHX2 | |
| SCHEMBL24193598 | 0.79 | KEAP1 (0.60) | KEAP1NFE2L2HDAC3HDAC4HDAC1 | |
| SCHEMBL19473289 | 0.78 | SAT1 (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL8848096 | 0.78 | NAAA (0.61) | KEAP1NFE2L2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5139914-A | — | — | None | — | — | JP | disclosed |
| JP-H05139914-A | EXTERMINATING AGENT FOR ARTHROPOD | DAICEL CHEM IND LTD | 1993-06-08 | — | — | JP | disclosed |