Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.71 |
| ▸ | CTSK | P43235 | 5/20 | 0.71 |
| ▸ | ACE | P12821 | 1/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 4/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310547 | 1.00 | CTSS (0.71) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL231981 | 1.00 | CTSS (0.71) | CTSSCTSKACEITGB3ITGA2B | |
| Benzene SCHEMBL6474758 | 0.99 | CTSS (0.70) | CTSSCTSKACEITGB3ITGA2B | |
| Benzene SCHEMBL3925161 | 0.99 | CTSS (0.70) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL28630396 | 0.95 | CTSS (0.72) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL29824479 | 0.91 | CTSS (0.68) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL28486021 | 0.91 | CTSS (0.61) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL7656189 | 0.91 | PPARA (0.69) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL10380744 | 0.90 | ACE (0.64) | CTSSCTSKACEITGB3ITGA2B | |
| SCHEMBL3270946 | 0.90 | CTSS (0.60) | CTSSCTSKACEITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776555-B | Difunctional D-amino acid modified opioid peptide compound and synthetic method and application thereof | 王锐 | 2023-10-13 | — | — | CN | claimed |
| WO-2020252713-A1 | MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江智达药业有限公司 | 2020-12-24 | — | — | WO | claimed |
| CN-106967151-B | Multi-site combination modified endomorphin analogue and synthesis and application thereof | 兰州大学 | 2020-08-11 | — | — | CN | claimed |
| CN-110776555-A | Bifunctional D-amino acid modified opioid peptide compound and synthesis method and application thereof | 王锐 | 2020-02-11 | — | — | CN | claimed |
| CN-110201182-A | A kind of taxol-DHA- dextran coupling polymer and its synthetic method and application | 山东大学 | 2019-09-06 | — | — | CN | claimed |
| CN-109897087-A | A kind of phosphated peptide section and protein-enriched methods and applications | 中国科学院大连化学物理研究所 | 2019-06-18 | — | — | CN | claimed |
| CN-105848771-B | High-speed centrifugal mixing arrangement and application method | 迪美公司 | 2018-07-10 | — | — | CN | claimed |
| CN-105848771-A | High-speed centrifugal mixing devices and methods of use | 迪美公司 | 2016-08-10 | — | — | CN | claimed |
| CN-104877005-A | Non-natural amino acid modified endomorphin-1 analogue as well as synthesis method and application thereof | UNIV LANZHOU | 2015-09-02 | — | — | CN | claimed |
| CN-103214552-B | Synthesis and application of multi-site modified endomorphin-1 analogue | UNIV LANZHOU | 2015-01-21 | — | — | CN | claimed |
| CN-102558297-B | Endomorphin-1 analogue modified by alpha-alkenyl-beta-amino acid and composition and application thereof | UNIV LANGZHOU | 2013-07-17 | — | — | CN | claimed |
| WO-2013001088-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL) TYROSINE | PIRAMAL IMAGING SA (CH) | 2013-01-03 | — | — | WO | claimed |
| CN-102558297-A | Endomorphin-1 analogue modified by alpha-alkenyl-beta-amino acid and composition and application thereof | UNIV LANGZHOU | 2012-07-11 | — | — | CN | claimed |
| US-20120004183-A1 | Unnatural reactive amino acid genetic code additions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-01-05 | — | — | US | claimed |
| EP-1636340-A4 | UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS | SCRIPPS RESEARCH INST (US) | 2009-02-11 | — | — | EP | claimed |
| US-20060246509-A1 | protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors | THE SCRIPPS RESEARCH INSTITUTE | 2006-11-02 | — | — | US | claimed |
| EP-1636340-A2 | UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS | The Scripps Research Institute (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005003294-A2 | UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-01-13 | — | — | WO | claimed |
| US-20040265952-A1 | protein containing a modified amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug that carries an alkynyl or azido group; translation biochemistry in eukaryotic cells; gene expression inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-12-30 | — | — | US | claimed |
| EP-0049500-B1 | TYROSINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN THE SYNTHESIS OF PEPTIDES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1984-02-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246509-A1 | protein containing an amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug by a [3+2] cycloaddition; translation biochemistry in eukaryotic cells; gene expression inhibitors | AARS1, ASNS, KARS1 | CTSS 1060/4885CTSK 3878/4885ACE 1326/4885 |
| US-20120004183-A1 | Unnatural reactive amino acid genetic code additions | AARS1, NSUN3, OSGEP | CTSS 974/4885CTSK 3379/4885ACE 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.