SCHEMBL9502548

SCHEMBL9502548

CCC(C)c1c(F)c(F)c(-c2c(F)c(F)c(O)c(F)c2F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
TSHR P16473 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14787971 0.94 ESR1 (0.36) ESR1TSHRUSP2ALDH1A1GAA
SCHEMBL9503297 0.87 PKM (0.32) PKM
SCHEMBL23642371 0.85 TSHR (0.35) ESR1TSHRUSP2ALDH1A1GAA
SCHEMBL25589444 0.83
SCHEMBL17904750 0.82 PKM (0.32) TSHRALDH1A1PKM
SCHEMBL107647 0.79 PKM (0.35) TSHRPKM
SCHEMBL11996901 0.75
SCHEMBL12522562 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL18790927 0.73
SCHEMBL3863935 0.73 ESR1 (0.33) ESR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364548-B1 OCTAFLUOROBIPHENYLS MERCK PATENT GmbH (DE) 1993-06-09 EP disclosed