SCHEMBL9502581

SCHEMBL9502581

Nc1c(O)cccc1O.Nc1ccc(O)cc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.48
CYP3A4 P08684 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TSHR P16473 1/20 0.46
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 3/20 0.43
CA2 P00918 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 3/20 0.43
ALDH1A1 P00352 2/20 0.43
CA1 P00915 2/20 0.43
CA7 P43166 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
G6PD P11413 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29458062 0.86
SCHEMBL593274 0.86
Hydrochloric Acid SCHEMBL183345 0.84 ALOX15 (0.59) ALOX15CYP3A4HSD17B10TSHRKDM4E
Hydrochloric Acid SCHEMBL30403038 0.84 ALOX15 (0.59) ALOX15CYP3A4HSD17B10TSHRKDM4E
Water SCHEMBL6757210 0.84 ALOX15 (0.59) ALOX15CYP3A4HSD17B10TSHRKDM4E
Hydrochloric Acid SCHEMBL1119370 0.81 ALOX15 (0.56) ALOX15CYP3A4HSD17B10TSHRKDM4E
SCHEMBL69654 0.78
Hydrochloric Acid SCHEMBL766671 0.75 G6PD (0.54) ALOX15CYP3A4HSD17B10TSHRKDM4E
Questiomycin B SCHEMBL7457859 0.74 ALOX15 (0.65) ALOX15CYP3A4HSD17B10TSHRKDM4E
Questiomycin B SCHEMBL7603625 0.73 ALOX15 (0.71) ALOX15CYP3A4HSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312931-B1 PROCESS FOR THE PREPARATION OF AMINO-1,3 BENZENEDIOL THE DOW CHEMICAL COMPANY (US) 1993-04-21 EP claimed