Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.57 |
| ▸ | KLK1 | P06870 | 2/20 | 0.57 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501872 | 0.89 | KDM4E (0.55) | KDM4ELDHAALDH1A1HPGDPOLB | |
| SCHEMBL13612581 | 0.84 | ALDH1A1 (0.65) | PLGKLK1KLK6KDM4EALDH1A1 | |
| SCHEMBL3541419 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL14880160 | 0.81 | KDM4E (0.53) | PLGKLK1KLK6KDM4EALDH1A1 | |
| SCHEMBL11199463 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL29427197 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24895107 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL9620963 | 0.79 | MAPT (0.56) | KDM4ELDHAALDH1A1HPGDPOLB | |
| SCHEMBL2510203 | 0.79 | CDC25B (0.64) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL8668029 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1HPGDPOLBABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |