Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502659 | 0.89 | PLG (0.57) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL21591456 | 0.87 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL9505574 | 0.84 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL9178555 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL6414851 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL13612575 | 0.83 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL9620963 | 0.80 | MAPT (0.56) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL31387888 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL3327762 | 0.80 | MTNR1A (0.70) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL7988819 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |