Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660324 | 0.77 | CYP2C19 (0.53) | KCNN4CYP2C19HIF1AKMT2AMTNR1A | |
| SCHEMBL27839162 | 0.77 | KCNN4 (0.58) | KCNN4CYP2C19HIF1ASRCKMT2A | |
| SCHEMBL1593582 | 0.77 | CYP2C19 (0.53) | KCNN4CYP2C19HIF1AKMT2AMTNR1A | |
| SCHEMBL5855770 | 0.74 | CYP2C19 (0.46) | KCNN4CYP2C19HIF1AKMT2AMTNR1A | |
| SCHEMBL27708172 | 0.73 | CYP2C19 (0.49) | KCNN4CYP2C19HIF1AKMT2AMTNR1A | |
| SCHEMBL1926066 | 0.73 | CYP2C19 (0.45) | KCNN4CYP2C19HIF1AKMT2AMTNR1A | |
| SCHEMBL9179352 | 0.72 | CYP2C19 (0.41) | KCNN4CYP2C19HIF1AMTNR1AMTNR1B | |
| SCHEMBL11222661 | 0.72 | ALDH1A1 (0.51) | KCNN4CYP2C19HIF1ASRCKMT2A | |
| SCHEMBL17825682 | 0.72 | CYP2C19 (0.47) | KCNN4CYP2C19HIF1AKMT2AMEN1 | |
| SCHEMBL8130212 | 0.72 | CHRM2 (0.45) | CYP2C19HIF1AKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301877-B1 | A METHOD OF DEPROTECTION OF 3-AMINO AZETIDINONES | ELI LILLY AND COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0301877-A1 | A method of deprotection of 3-amino azetidinones | ELI LILLY AND COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |