Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12082786 | 0.85 | NQO1 (0.50) | KDM4EKMT2AL3MBTL1LTA4HCA12 | |
| SCHEMBL13261015 | 0.82 | KDM4E (0.64) | KDM4EKMT2AL3MBTL1LTA4HCA12 | |
| SCHEMBL9931911 | 0.81 | KDM4E (0.46) | KDM4EKMT2AL3MBTL1THRATHRB | |
| SCHEMBL3787950 | 0.79 | CSNK2A1 (0.62) | KDM4EKMT2AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL5672530 | 0.79 | DRD2 (0.56) | KDM4EKMT2ALTA4HCA12CA1 | |
| SCHEMBL3717444 | 0.78 | LTA4H (0.50) | KDM4EKMT2ATHRATHRBLTA4H | |
| SCHEMBL469903 | 0.78 | MAPT (0.51) | KDM4EKMT2AL3MBTL1LTA4HCA12 | |
| SCHEMBL256301 | 0.78 | KDM4E (0.46) | KDM4EKMT2AL3MBTL1THRATHRB | |
| SCHEMBL10624733 | 0.76 | KDM4E (0.45) | KDM4EKMT2AL3MBTL1THRATHRB | |
| SCHEMBL10648594 | 0.76 | PDK2 (0.38) | KDM4EKMT2AL3MBTL1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544732-A1 | IMPROVED PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | WEHRENBERG, Peter K. (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003447-A1 | IMPROVED PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | WEHRENBERG PETER K (US) | 1992-03-05 | — | — | WO | disclosed |
| US-5081272-A | PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4727178-A | Process for preparing phosphorodichloridothiolate | STAUFFER CHEMICAL CO. (US) | 1988-02-23 | — | — | US | disclosed |
| US-4056581-A | Process for the preparation of phosphorodichloridothiolates | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | disclosed |