Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578378 | 0.85 | SKP2 (0.55) | SKP2 | |
| SCHEMBL10733889 | 0.85 | SKP2 (0.47) | SKP2NPC1HPGDMAPK1HTT | |
| SCHEMBL13663812 | 0.76 | SKP2 (0.58) | SKP2NPC1HPGDMAPK1HTT | |
| SCHEMBL8415231 | 0.76 | CYP19A1 (0.45) | SKP2RAB9A | |
| SCHEMBL9502793 | 0.76 | ACACB (0.44) | RAB9A | |
| SCHEMBL2090838 | 0.74 | SLC6A4 (0.40) | — | |
| SCHEMBL97681 | 0.73 | CA2 (0.54) | SKP2HPGDCYP3A4 | |
| SCHEMBL12593194 | 0.71 | SKP2 (0.39) | SKP2NPC1HPGDRAB9A | |
| SCHEMBL12593180 | 0.71 | ICAM1 (0.44) | SKP2 | |
| SCHEMBL12856182 | 0.71 | PPARG (0.55) | SKP2HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |