Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | PRNP | P04156 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 8/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505833 | 0.86 | DHODH (0.50) | DHODHALDH1A1MAPT | |
| SCHEMBL9502242 | 0.86 | DHODH (0.63) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL8794351 | 0.84 | DHODH (0.49) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL17594351 | 0.83 | PTGFR (0.53) | POLBPRNPALDH1A1PTGFRRXFP1 | |
| SCHEMBL18075841 | 0.81 | DHODH (0.51) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL17594288 | 0.81 | PTGFR (0.51) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL17593967 | 0.81 | PTGFR (0.52) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL17594086 | 0.80 | PTGFR (0.50) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL18075787 | 0.80 | PTGFR (0.53) | POLBDHODHPRNPALDH1A1PTGFR | |
| SCHEMBL17593897 | 0.79 | PTGFR (0.53) | POLBPRNPALDH1A1PTGFRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | claimed |