Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.50 |
| ▸ | TACR3 | P29371 | 7/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502835 | 0.86 | POLB (0.49) | DHODHALDH1A1MAPT | |
| SCHEMBL9502807 | 0.84 | DHODH (0.64) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL8794990 | 0.82 | DHODH (0.51) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL27583476 | 0.82 | PDE10A (0.60) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL5498214 | 0.81 | PDE10A (0.62) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL18075813 | 0.80 | PDE10A (0.61) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL5497084 | 0.79 | DHODH (0.60) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL27563380 | 0.76 | PDE10A (0.44) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL27704347 | 0.75 | PDE10A (0.43) | DHODHTACR3PDE10ATSHRLMNA | |
| SCHEMBL377269 | 0.75 | PDE10A (0.53) | PDE10ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | claimed |