Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511199 | 0.92 | LTA4H (0.66) | LTA4HPLA2G2AFFAR1FFAR4MAOB | |
| SCHEMBL15264618 | 0.88 | TAAR1 (0.46) | FFAR1FFAR4MAOBTAAR1 | |
| SCHEMBL9869869 | 0.87 | FFAR1 (0.53) | LTA4HPLA2G2AFFAR1FFAR4MAOB | |
| Hydrochloric Acid SCHEMBL4379970 | 0.86 | MAOB (0.46) | FFAR1FFAR4MAOBTAAR1 | |
| SCHEMBL9713896 | 0.82 | FFAR4 (0.59) | LTA4HPLA2G2AFFAR1FFAR4CACNA1B | |
| SCHEMBL15923332 | 0.81 | PRSS1 (0.47) | — | |
| SCHEMBL13886637 | 0.81 | LTA4H (0.81) | LTA4HPLA2G2ATAAR1 | |
| SCHEMBL6290496 | 0.80 | ALDH1A1 (0.54) | LTA4HFFAR1FFAR4MAOBMMP2 | |
| SCHEMBL6289347 | 0.80 | ALDH1A1 (0.54) | LTA4HFFAR1FFAR4MAOBMMP2 | |
| SCHEMBL506288 | 0.80 | ST14 (0.62) | MAOBTAAR1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350688-B1 | CYCLOPROPANE CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT PESTS | BASF Aktiengesellschaft (DE) | 1993-04-14 | — | — | EP | disclosed |
| EP-0350688-A2 | Cyclopropane carboxamides, process for their preparation and their use to combat pests | BASF Aktiengesellschaft (DE) | 1990-01-17 | — | — | EP | disclosed |