Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL10984219 | 0.91 | ALOX15 (0.56) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| Itaconate SCHEMBL28337916 | 0.83 | HSD17B10 (0.48) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| SCHEMBL1300687 | 0.83 | ALDH1A1 (0.44) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| SCHEMBL60440 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| SCHEMBL1809603 | 0.81 | ALOX15 (0.57) | ALDH1A1ALOX15HSD17B10TET2TET3 | |
| SCHEMBL11694969 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| Ammonia Solution, Strong SCHEMBL27793329 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| Ethylene SCHEMBL27718140 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| SCHEMBL11696832 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10EGLN1TET2 | |
| SCHEMBL353003 | 0.79 | ALDH1A1 (0.41) | ALDH1A1ALOX15HSD17B10EGLN1TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135280-B1 | NEW POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREBY | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1993-05-12 | — | — | EP | disclosed |
| US-4581429-A | Polymerization process and polymers produced thereby | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1986-04-08 | — | — | US | disclosed |
| EP-0135280-A2 | New polymerization process and polymers produced thereby | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1985-03-27 | — | — | EP | disclosed |