Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502985 | 0.74 | SMAD3 (0.37) | — | |
| SCHEMBL9506050 | 0.73 | CES1 (0.37) | CES1TYMSTGM2GRIA1CACNG8 | |
| SCHEMBL8572771 | 0.67 | EDNRB (0.34) | — | |
| SCHEMBL8889709 | 0.65 | NPC1 (0.33) | — | |
| SCHEMBL11251392 | 0.64 | CES1 (0.39) | CES1TGM2GRIA1CACNG8PBRM1 | |
| SCHEMBL675984 | 0.64 | CFTR (0.48) | TYMSPOLB | |
| SCHEMBL9504859 | 0.62 | CES1 (0.36) | CES1 | |
| SCHEMBL8131514 | 0.60 | CES1 (0.36) | CES1TGM2 | |
| SCHEMBL11179059 | 0.60 | CES1 (0.43) | CES1TGM2GRIA1CACNG8PBRM1 | |
| SCHEMBL542 | 0.60 | TSHR (0.52) | CES1TYMSGRIA1CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |