Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139378 | 0.75 | NSD2 (0.41) | CES1TYMS | |
| SCHEMBL9502912 | 0.73 | CES1 (0.37) | CES1TYMSTGM2GRIA1CACNG8 | |
| SCHEMBL9502953 | 0.72 | CES1 (0.39) | CES1TYMS | |
| SCHEMBL2235308 | 0.72 | CES1 (0.39) | CES1TYMS | |
| SCHEMBL8649408 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL542 | 0.64 | TSHR (0.52) | CES1ADORA2ATYMSRETGRK5 | |
| SCHEMBL29555800 | 0.64 | TSHR (0.52) | CES1ADORA2ATYMSRETGRK5 | |
| SCHEMBL1477149 | 0.60 | CES1 (0.50) | CES1ADORA2AGRIA1 | |
| SCHEMBL895684 | 0.59 | CES1 (0.56) | CES1RETGRK5TYRO3DYRK1B | |
| SCHEMBL5111725 | 0.59 | PGR (0.52) | CES1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |