Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830149 | 0.84 | FDPS (0.32) | FDPS | |
| SCHEMBL8193965 | 0.80 | FDPS (0.39) | FDPSLMNAGGPS1LPAR3LPAR1 | |
| SCHEMBL4828598 | 0.78 | FDPS (0.41) | FDPSLMNAGGPS1LPAR3LPAR1 | |
| SCHEMBL9125627 | 0.74 | FDPS (0.34) | FDPSLMNAGGPS1LPAR3LPAR1 | |
| SCHEMBL9126175 | 0.74 | FDPS (0.38) | FDPSLMNAGGPS1LPAR3LPAR1 | |
| SCHEMBL18813385 | 0.72 | LPAR3 (0.34) | FDPSGGPS1LPAR3LPAR1LPAR2 | |
| SCHEMBL8722288 | 0.72 | PPARD (0.35) | FDPSGGPS1LPAR3LPAR1LPAR2 | |
| SCHEMBL10700021 | 0.72 | FDPS (0.33) | FDPSGGPS1LPAR3LPAR1LPAR2 | |
| SCHEMBL3482322 | 0.71 | HCAR2 (0.34) | FDPS | |
| SCHEMBL8334216 | 0.71 | FDPS (0.33) | FDPSLMNAGGPS1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |