Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.59 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506162 | 1.00 | ACAT1 (0.59) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9502971 | 1.00 | ACAT1 (0.59) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9502156 | 1.00 | ACAT1 (0.59) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9502436 | 0.95 | ACAT1 (0.61) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9503003 | 0.94 | ACAT1 (0.54) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9506060 | 0.92 | ACAT1 (0.69) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9503719 | 0.92 | ACAT1 (0.69) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9505475 | 0.92 | ACAT1 (0.69) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9502216 | 0.92 | ACAT1 (0.50) | ACAT1CETPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9503039 | 0.92 | ACAT1 (0.50) | ACAT1CETPNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |