Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.45 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.45 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502971 | 0.94 | ACAT1 (0.59) | ACAT1SOAT1ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9502156 | 0.94 | ACAT1 (0.59) | ACAT1SOAT1ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9506162 | 0.94 | ACAT1 (0.59) | ACAT1SOAT1ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9502927 | 0.94 | ACAT1 (0.59) | ACAT1SOAT1ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9505428 | 0.93 | ACAT1 (0.62) | ACAT1SOAT2SOAT1PSMB11PSMA7 | |
| SCHEMBL9505430 | 0.93 | ACAT1 (0.62) | ACAT1SOAT2SOAT1PSMB11PSMA7 | |
| SCHEMBL9502444 | 0.90 | ACAT1 (0.58) | ACAT1LPAR1SOAT2SOAT1PSMB11 | |
| SCHEMBL9502440 | 0.90 | ACAT1 (0.58) | ACAT1LPAR1SOAT2SOAT1PSMB11 | |
| SCHEMBL9502436 | 0.89 | ACAT1 (0.61) | ACAT1ALDH1A1NPC1CYP1A2CYP2C9 | |
| SCHEMBL9505475 | 0.87 | ACAT1 (0.69) | ACAT1ALDH1A1NPC1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |