Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321059 | 0.85 | SLC22A12 (0.53) | SLC22A12ARERAP1TP53GRM4 | |
| SCHEMBL9363640 | 0.83 | SLC22A12 (0.43) | SLC22A12ARERAP1TP53LMNA | |
| SCHEMBL9503090 | 0.81 | SLC22A12 (0.43) | SLC22A12ARERAP1RORC | |
| SCHEMBL9500825 | 0.81 | SLC22A12 (0.45) | SLC22A12ARERAP1TP53LMNA | |
| SCHEMBL9368636 | 0.79 | SLC22A12 (0.41) | SLC22A12ARERAP1TP53LMNA | |
| SCHEMBL9363645 | 0.79 | SLC22A12 (0.47) | SLC22A12ARERAP1TP53GRM4 | |
| SCHEMBL9367199 | 0.77 | SLC22A12 (0.45) | SLC22A12ARERAP1TP53LMNA | |
| SCHEMBL9363435 | 0.77 | SLC22A12 (0.45) | SLC22A12ARERAP1TP53GRM4 | |
| SCHEMBL9499786 | 0.76 | KMT2A (0.46) | ARMAPT | |
| SCHEMBL9368675 | 0.76 | AR (0.43) | SLC22A12ARGRM4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| US-5130119-A | Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |