Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 5/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363645 | 0.88 | SLC22A12 (0.47) | SLC22A12ARIDO1IDH2ERAP1 | |
| SCHEMBL9321059 | 0.85 | SLC22A12 (0.53) | SLC22A12ARIDH2ERAP1GRM4 | |
| SCHEMBL9368636 | 0.85 | SLC22A12 (0.41) | SLC22A12ARIDO1ERAP1LMNA | |
| SCHEMBL9363483 | 0.82 | SLC22A12 (0.44) | SLC22A12ARIDH2ERAP1GRM4 | |
| SCHEMBL9363435 | 0.81 | SLC22A12 (0.45) | SLC22A12ARIDH2ERAP1GRM4 | |
| SCHEMBL9363762 | 0.81 | RORC (0.44) | SLC22A12ARGCGRKCNQ3KCNQ2 | |
| SCHEMBL9367106 | 0.79 | KMT2A (0.47) | ARGCGRIDH2LMNAGAA | |
| SCHEMBL9503090 | 0.79 | SLC22A12 (0.43) | SLC22A12ARERAP1GAAPOLB | |
| SCHEMBL9363653 | 0.78 | MAPT (0.50) | SLC22A12ERAP1LMNAMAPTHTT | |
| SCHEMBL9503137 | 0.77 | SLC22A12 (0.50) | SLC22A12ARERAP1GRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| EP-0447013-A1 | Fluorobenzene sulphonamides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |