Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.47 |
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.37 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715152 | 0.89 | MMP1 (0.41) | MMP3MMP1MMP2CAPN1MMP9 | |
| SCHEMBL9503972 | 0.83 | MMP3 (0.51) | MMP3MMP1MMP2CAPN1CPA1 | |
| SCHEMBL9503983 | 0.83 | MMP3 (0.51) | MMP3MMP1MMP2CAPN1CPA1 | |
| SCHEMBL9503299 | 0.83 | MMP3 (0.62) | MMP3MMP1MMP2CPA1CPA2 | |
| SCHEMBL9503311 | 0.83 | MMP3 (0.62) | MMP3MMP1MMP2CPA1CPA2 | |
| SCHEMBL9503152 | 0.74 | MMP1 (0.55) | MMP3MMP1MMP2 | |
| SCHEMBL9503126 | 0.74 | MMP1 (0.55) | MMP3MMP1MMP2 | |
| SCHEMBL21553669 | 0.72 | F2 (0.46) | MMP3MMP1CPA1CPA2CPA4 | |
| SCHEMBL22930154 | 0.72 | CAPN1 (0.47) | MMP3MMP1CAPN1CPA1CPA2 | |
| SCHEMBL9506233 | 0.72 | MMP3 (0.71) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| EP-0276436-A1 | Phosphinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-08-03 | — | — | EP | disclosed |