Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.67 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.67 |
| ▸ | MRGPRX4 | Q96LA9 | 16/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462073 | 0.84 | RXRA (0.76) | NR4A2NR4A1NR4A3SMN1; SMN2RAB9A | |
| SCHEMBL9853926 | 0.84 | MRGPRX4 (0.62) | NR4A2NR4A1NR4A3MRGPRX4TP53 | |
| SCHEMBL6836371 | 0.82 | MRGPRX4 (0.75) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| Hydrochloric Acid SCHEMBL6843292 | 0.81 | MRGPRX4 (0.73) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL7052396 | 0.81 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MRGPRX4SMN1; SMN2 | |
| SCHEMBL4406160 | 0.81 | NR4A2 (0.87) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL4138759 | 0.81 | NR4A2 (0.81) | NR4A2MRGPRX4TP53PKMNFKB1 | |
| SCHEMBL22480871 | 0.80 | MRGPRX4 (1.00) | NR4A2NR4A1NR4A3MRGPRX4 | |
| SCHEMBL22480781 | 0.80 | MRGPRX4 (1.00) | NR4A2MRGPRX4 | |
| SCHEMBL22481056 | 0.78 | MRGPRX4 (1.00) | NR4A2MRGPRX4TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288305-B1 | DI-T-BUTYLPHENYL ALKYL AND BENZYL ETHERS | RIKER LABORATORIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4973731-A | Di-t-butylphenyl alkyl and benzyl ether nitriles | RIKER LABORATORIES, INC. (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0288305-A1 | Di-t-butylphenyl alkyl and benzyl ethers | RIKER LABORATORIES, INC. (US) | 1988-10-26 | — | — | EP | disclosed |