Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 17/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854008 | 0.85 | RXRA (0.63) | SMN1; SMN2RAB9ANR4A2NR4A1NR4A3 | |
| SCHEMBL9503382 | 0.84 | NR4A2 (0.67) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL22480752 | 0.80 | MRGPRX4 (0.76) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL11776437 | 0.80 | MEN1 (0.52) | NR4A2NR4A1NR4A3 | |
| SCHEMBL6836371 | 0.80 | MRGPRX4 (0.75) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL6843292 | 0.79 | MRGPRX4 (0.73) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL4406160 | 0.78 | NR4A2 (0.87) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL4138759 | 0.78 | NR4A2 (0.81) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL22480542 | 0.77 | MRGPRX4 (1.00) | MRGPRX4TP53NFKB1NFKB2RELA | |
| SCHEMBL13976376 | 0.77 | MRGPRX4 (0.41) | MRGPRX4TP53PKMNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |