Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.53 |
| ▸ | BCL2 | P10415 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368181 | 0.80 | TP53 (0.63) | TP53HTTMRGPRX4NR4A2FOLH1 | |
| SCHEMBL10420779 | 0.79 | MCL1 (0.47) | MCL1BCL2TP53HTTMRGPRX4 | |
| SCHEMBL31717939 | 0.79 | MEN1 (0.66) | TP53HTTMRGPRX4NR4A2FOLH1 | |
| SCHEMBL10564526 | 0.79 | BCL2 (0.53) | MCL1BCL2TP53HTTMRGPRX4 | |
| SCHEMBL4452776 | 0.78 | HIF1A (0.61) | MCL1TP53HTTMRGPRX4NR4A2 | |
| SCHEMBL8783125 | 0.77 | SOD1 (0.49) | MCL1BCL2HTTNR4A2NR4A1 | |
| SCHEMBL8591392 | 0.77 | BCL2 (0.38) | MCL1BCL2TP53HCAR2NR4A2 | |
| SCHEMBL8591394 | 0.77 | BCL2 (0.38) | MCL1BCL2TP53HCAR2NR4A2 | |
| SCHEMBL9503382 | 0.76 | NR4A2 (0.67) | TP53MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL5988399 | 0.76 | TP53 (0.56) | TP53HTTMRGPRX4NR4A2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288305-B1 | DI-T-BUTYLPHENYL ALKYL AND BENZYL ETHERS | RIKER LABORATORIES, INC. (US) | 1993-08-04 | — | — | EP | claimed |
| EP-0288305-A1 | Di-t-butylphenyl alkyl and benzyl ethers | RIKER LABORATORIES, INC. (US) | 1988-10-26 | — | — | EP | claimed |
| JP-1034943-A | — | — | None | — | — | JP | disclosed |
| EP-0288305-B1 | DI-T-BUTYLPHENYL ALKYL AND BENZYL ETHERS | RIKER LABORATORIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4973731-A | Di-t-butylphenyl alkyl and benzyl ether nitriles | RIKER LABORATORIES, INC. (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0288305-A1 | Di-t-butylphenyl alkyl and benzyl ethers | RIKER LABORATORIES, INC. (US) | 1988-10-26 | — | — | EP | disclosed |