Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381961 | 1.00 | TSHR (0.51) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL11249134 | 1.00 | TSHR (0.51) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL4267988 | 0.88 | TSHR (0.54) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL4267985 | 0.88 | TSHR (0.54) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL4417046 | 0.87 | LMNA (0.53) | KDM4ELMNANPC1RAB9AHTT | |
| SCHEMBL7227572 | 0.87 | LMNA (0.53) | KDM4ELMNANPC1RAB9AHTT | |
| SCHEMBL7382317 | 0.87 | RAB9A (0.43) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL7379752 | 0.84 | TSHR (0.54) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL7379755 | 0.84 | TSHR (0.54) | TSHRKDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL734962 | 0.82 | TSHR (0.56) | TSHRKDM4ESMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589101-A | Herbicides containing substituted thien-3-ylsulfonylamino (thio) carbonyltriazolin (thi) one compounds | BAYER CROPSCIENCE GMBH (DE) | 2005-03-02 | — | — | CN | disclosed |
| EP-0333282-B1 | PREPARATION OF OPTICALLY ACTIVE N-SUBSTITUTED ALANINE HERBICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-06-09 | — | — | EP | disclosed |
| EP-0333282-A1 | Preparation of optically active N-substituted alanine herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-09-20 | — | — | EP | disclosed |