Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.30 |
| ▸ | PKM | P14618 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505628 | 0.78 | SMN1; SMN2 (0.53) | KDM4EGAAMAPTIDO1SMN1; SMN2 | |
| SCHEMBL3817613 | 0.78 | GAA (0.43) | KDM4EGAAMAPTAGTR1IDO1 | |
| SCHEMBL9224524 | 0.73 | P2RY1 (0.43) | KDM4EGAAMAPTIDO1SMN1; SMN2 | |
| SCHEMBL5537146 | 0.71 | KDM4E (0.34) | KDM4EMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17088286 | 0.67 | KDM4E (0.34) | KDM4EGAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9501596 | 0.67 | MEN1 (0.34) | KDM4EGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10968419 | 0.67 | — | — | |
| SCHEMBL14224022 | 0.66 | NPC1 (0.51) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL18387206 | 0.62 | MAPK1 (0.36) | KDM4EGAALMNAALDH1A1NPC1 | |
| SCHEMBL11224659 | 0.60 | GAA (0.31) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316731-B1 | AZO DYES FROM 2-HYDRAZINOTHIAZOLE, THEIR USE IN DYEING AND PRINTING FIBRE MATERIALS, AND IN SUBLIMATION TRANSFER PRINTING | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0316731-A2 | Azo dyes from 2-hydrazinothiazole, their use in dyeing and printing fibre materials, and in sublimation transfer printing | BAYER AG (DE) | 1989-05-24 | — | — | EP | disclosed |