Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503452 | 1.00 | CYP2C9 (0.41) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9507157 | 0.91 | DRD2 (0.38) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9507163 | 0.91 | DRD2 (0.38) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503689 | 0.86 | DRD2 (0.43) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9503686 | 0.86 | DRD2 (0.43) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9631064 | 0.82 | DRD2 (0.41) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9631071 | 0.82 | DRD2 (0.41) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9631057 | 0.82 | DRD2 (0.41) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8727511 | 0.82 | CYP2C9 (0.43) | CYP2C9DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8031381 | 0.78 | KMT2A (0.44) | CYP2C9DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387032-B1 | TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | CHISSO CORP (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |