Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507163 | 1.00 | DRD2 (0.38) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503452 | 0.91 | CYP2C9 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503457 | 0.91 | CYP2C9 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10345353 | 0.79 | DRD2 (0.39) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503686 | 0.79 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503689 | 0.79 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9631071 | 0.74 | DRD2 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9631064 | 0.74 | DRD2 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9631057 | 0.74 | DRD2 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503640 | 0.74 | CYP1A2 (0.41) | MAPTCYP1A2KMT2APTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387032-B1 | TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | CHISSO CORP (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |