SCHEMBL950350

SCHEMBL950350

CCC(SC)c1nccn1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 2/20 0.41
CYP2D6 P10635 1/20 0.36
LPO P22079 1/20 0.36
MAPT P10636 2/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
HTT P42858 1/20 0.34
KMT2A Q03164 3/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
FGB P02675 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11384751 0.84 KDM4E (0.40) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL14148932 0.76 L3MBTL1 (0.46) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL4057810 0.76 KDM4E (0.50) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL950779 0.75 KDM4E (0.44) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL13663805 0.75 L3MBTL1 (0.45) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL8241575 0.75 L3MBTL1 (0.45) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL27942970 0.73 L3MBTL1 (0.47) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL27679740 0.73 L3MBTL1 (0.47) L3MBTL1KDM4ECYP2D6LPOMAPT
SCHEMBL14665069 0.73 KDM4E (0.51) L3MBTL1KDM4ECYP2D6LPOMAPT
Hydrochloric Acid SCHEMBL25338117 0.72 L3MBTL1 (0.46) L3MBTL1KDM4ECYP2D6LPOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110021483-A1 Platinum (IV) Complexes PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2011-01-27 US disclosed
EP-2170913-A1 PLATINUM (IV) COMPLEXES Platco Technologies (Proprietary) Limited (ZA) 2010-04-07 EP disclosed
WO-2008155727-A1 PLATINUM (IV) COMPLEXES PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) 2008-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021483-A1 Platinum (IV) Complexes OTC, OAT, SLC25A11 L3MBTL1 2167/4885KDM4E 3423/4885CYP2D6 1078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.