Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635146 | 0.68 | — | — | |
| SCHEMBL21461250 | 0.68 | CHRM2 (0.45) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| SCHEMBL18049064 | 0.65 | CHRM2 (0.64) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| Arecoline SCHEMBL44065 | 0.65 | CHRM2 (1.00) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| Methoxyamine SCHEMBL21461251 | 0.65 | CHRM2 (0.46) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| Arecoline SCHEMBL527735 | 0.64 | BLM (1.00) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| Arecoline SCHEMBL3057863 | 0.64 | CHRM2 (0.96) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| SCHEMBL2608725 | 0.64 | — | — | |
| SCHEMBL9130174 | 0.64 | CHRM2 (0.48) | CHRM2CHRM5CHRM1LMNACHRM4 | |
| SCHEMBL15800663 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546005-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-06-16 | — | — | EP | claimed |
| WO-1992004323-A1 | 1,2,5,6-TETRAHYDROPYRIDINE OXIME DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | claimed |