Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1445912 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL29118179 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL532723 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL384201 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3261 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8059663 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9145494 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3266233 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL711064 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1331961 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784959-B | Buwa western medicine Process for the preparation of tam | 凯特立斯（深圳）科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119899136-A | Preparation method of intermediate N, N-dimethyl carbamic acid m-dimethyl amino phenyl ester | 浙江海昇药业股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119822941-A | Synthesis method of 2- (3-hydroxypropyl) -cyclododecanone | 万华化学集团股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-116217648-B | Preparation and purification method of melengestrol acetate | 湖南科益新生物医药有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-118620302-A | Wear-resistant flame-retardant cable material and preparation method thereof | 常州信息职业技术学院 | 2024-09-10 | — | — | CN | claimed |
| CN-117624274-B | Preparation method of eplerenone intermediate delta 9, 11-canrenone | 浙江晟创制药有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-118063412-A | Docetaxel derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-05-24 | — | — | CN | claimed |
| CN-118005706-A | Preparation method of 2',3' -dideoxynucleotide | 天津奥利芙生物技术有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117624274-A | Preparation method of eplerenone intermediate delta 9,11-canrenone | 浙江晟创制药有限公司 | 2024-03-01 | — | — | CN | claimed |
| EP-3778568-B1 | METHOD OF PREPARING HIGH CHIRAL PURITY LACTAM INTERMEDIATE AND BRIVARACETAM | YANGZHOU AORUITE PHARMACEUTICAL CO LTD (CN) | 2023-12-06 | — | — | EP | claimed |
| CN-103966905-A | Bamboo leaf-imitated uvioresistant antibacterial release paper and preparation method thereof | JIXIANGBAO TAICANG RELEASE MATERIAL TECHNOLOGY DEV CO LTD | 2014-08-06 | — | — | CN | claimed |
| CN-103952944-A | Method for preparing lotus leaf-imitated glassine release paper | JIXIANGBAO TAICANG MOLD RELEASE MATERIAL TECHNOLOGY DEV CO LTD | 2014-07-30 | — | — | CN | claimed |
| CN-103938495-A | Method for preparing matte antibacterial release paper | JIXIANGBAO TAICANG RELEASE MATERIAL TECHNOLOGY DEV CO LTD | 2014-07-23 | — | — | CN | claimed |
| CN-103924483-A | Method for preparing bamboo-leaf-imitated Glasin release paper | JIXIANGBAO TAICANG RELEASE MATERIAL TECHNOLOGY DEV CO LTD | 2014-07-16 | — | — | CN | claimed |
| CN-103275002-A | Preparation method of pelitinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-09-04 | — | — | CN | claimed |
| CN-103265482-A | Preparation method of bosutinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-103265530-A | Preparation method of neratinib | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-103242432-A | Method for synthesizing phosphoramidon by utilizing hydrogen phosphorous acid diester intermediate | UNIV JIANGXI NORMAL SCI & TECH | 2013-08-14 | — | — | CN | claimed |
| CN-103145604-A | Method for preparing ropinirole key intermediate | SHANGHAI AOBO BIO PHARMACEUTICAL TECH CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-103130704-A | Novel method for preparing 4-(2-ethoxy)-1,3-dihydro-2H-indole-2-ketone | SHANGHAI AOBO BIO PHARMACEUTICAL TECH CO LTD | 2013-06-05 | — | — | CN | claimed |